"I became insane, with long intervals of horrible sanity. During these fits of absolute unconsciousness, I drank--God only knows how often or how much. As a matter of course, my enemies referred the insanity to the drink rather than the drink to the insanity. I had, indeed, nearly abandoned all hope of a permanent cure, when I found one in the death of my wife. This I can and do endure as becomes a man. It was the horrible never-ending oscillation between hope and despair which I could not longer have endured, without total loss of reason."
--Edgar Allan Poe